An injection apparatus for sequentially injecting a patient with at least two medicaments may include a hand-held unit comprising a grip for being held by an operator, a single needle, a base unit coupled to the hand-held unit via at least one connecting tube, at least two containers for holding medicaments removably coupled to the base unit, and at least one pump. The at least one connecting tube can be flexible enough to enable easy maneuvering of the hand-held unit and rigid enough to prevent widening of the tube due to inner pressure when medicaments pass from the containers to the hand-held unit. The injection apparatus can be used to administer the at least two medicaments sequentially at different injection points.