Compositions, uses, kits and methods for reducing binge or compulsive eating are described herein. Methods may include administering an effective combination of a dosage of a bupropion or a pharmaceutically acceptable salt thereof, and a dosage of naltrexone or a pharmaceutically acceptable salt thereof. Methods may include identifying a patient who is overweight or obese and providing an effective combination of bupropion and naltrexone to the patient. Methods may include reducing a number of binge or compulsive eating events. Methods may include reducing severity of binge or compulsive eating events.本文描述用於降低暴食或強迫進食之組合物、用途、套組及方法。方法可包括投與安非他酮(bupropion)或其醫藥學上可接受之鹽之劑量及納曲酮(naltrexone)或其醫藥學上可接受之鹽之劑量的有效組合。方法可包括鑑定超重或肥胖患者且向該患者提供安非他酮及納曲酮之有效組合。方法可包括降低大量暴食或強迫進食事件。方法可包括降低暴食或強迫進食事件之嚴重性。