The Board of Regents of the University of Texas System
发明人:
Jinming GAO,Gang HUANG,Tian ZHAO,Baran D. SUMER,Xiankai SUN
申请号：
US16570337
公开号：
US20200087451A1
申请日:
2019.09.13
申请国别(地区):
US
年份:
2020
代理人:
摘要：
The present disclosure relates to polymers which contain a hydrophobic and hydrophilic segment which is sensitive to pH as well as a metal chelating group. In some aspects, the metal chelating group is chelated to a metal ion capable of positron emission. In some aspects, the polymers form a micelle which is sensitive to pH and results in a change in fluorescence based upon the particular pH. In some aspects, the disclosure also provides methods of using the polymers for the imaging of cellular or extracellular environment or delivering a drug.
