N-AROYLPHENYLALANINE DERIVATIVES, USE OF THE SAME, MEDICINAL PRODUCTS CONTAINING THE SAME.

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专利权人:

F HOFFMANN LA ROCHE AG

发明人:

LI CHEN,ROBERT WILLIAM GUTHRIE,TAI-NANG HUANG,KENNETH G HULL,ACHYTHARAO SIDDURI,JEFFERSON WRIGHT TILLEY

申请号：

BR9811730

公开号：

BR9811730B1

申请日:

1998.08.13

申请国别(地区):

BR

年份:

2014

代理人:

摘要：

Compounds of formula (1) as well as their salts and esters are disclosed wherein X, X', Z and Y are as described in the specification and which have activity as inhibitors of binding between VCAM-1 and cells expressing VLA-4. Such compounds are useful for treating diseases whose symptoms and/or damage are related to the binding of VCAM-1 to cells expressing VLA-4.

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