The apparatus (1) for the decapneization of blood, comprises: - a supply line (2) of the blood to be treated taken from a patient and at least a return line (5) able to transport the treated blood to the patient - at least an oxygenation device (3) and at least a filtering device (4) of the blood positioned between the supply line (2) and the return line (5) - first pumping means (8) able to convey the blood along the supply line (2) towards at least one of the oxygenation device (3) and the filtering device (4) where the first pumping means (8) are of the type of a centrifugal pump.