BENGT ANDERS BRUNMARK,CHIN YUNG HO,DANA L. JOHNSON,DONALD W. LUDOVICI,ERIC D. STROBEL,HWA KWO YEN,JAN L. SECHLER,JAY M. MEI,ROBERT A. GALEMMO JR,ROBERT W. TUMAN,STUART EMANUEL,UMAR MAHAROOF
申请号:
BR0311179
公开号:
BRPI0311179A2
申请日:
2003.05.13
申请国别(地区):
BR
年份:
2016
代理人:
摘要:
The invention is directed to N-substituted tricyclic 3-AMINOPYRAZOLE derivatives, which are useful as inhibitors of platelet-derived growth factor receptor (PDGF-R) kinase, and methods for the preparation of said derivatives. The present invention is further directed to pharmaceutical compositions comprising the compounds of the present invention and to methods for treating conditions such as tumors and other cell proliferative disorders.