HWANG, SANG YOUN,HUH, YONG HO,KIM, JIN YOUNG,HONG, SUNG HEE,CHOI, IN YOUNG,JUNG, SUNG YOUB,KWON, SE CHANG,KIM, DAE JIN,KIM, HYUN UK,JANG, MYUNG HYUN,KIM, SEUNG SU
申请号:
CA2901873
公开号:
CA2901873A1
申请日:
2014.02.26
申请国别(地区):
CA
年份:
2014
代理人:
摘要:
The present invention relates to: an insulin analog, wherein the insulin titer is reduced compared with a natural form and the binding force to an insulin receptor is reduced in order to increase the half-life of insulin in the blood; a conjugate, wherein the insulin analog and a carrier are connected; an extended release preparation containing the conjugate; and a method for preparing the conjugate.