Recombinant poxvirus vector expressing both rabies protein and OX40 protein and vaccine produced from said vector

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专利权人:

メリアル インコーポレイテッド

发明人:

メバション テショメ,ミンク ジュール マールテン,デイヴィッド フレデリック

申请号：

JP2014557782

公开号：

JP6260972B2

申请日:

2013.02.14

申请国别(地区):

JP

年份:

2018

代理人:

摘要：

The present invention provides vectors that contain and co-express in vivo or in vitro immunogenic polypeptides or antigens together with an OX40L polypeptide, which functions as a genetic adjuvant. Together, the immunogenic polypeptide and the OX40L polypeptide elicit an immune response in animal or human, which is greater than the immune response elicited by the immunogenic polypeptide alone. In a particular example, the invention provides vectors encoding a Rabies G immunogenic polypeptide and a canine OX40L genetic adjuvant, which vectors elicit strong immune responses in canine against rabies virus

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中国工程科技知识中心

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http://www.ckcest.cn/home/