ALLEGRETTI, MARCELLO,ARAMINI, ANDREA,BIANCHINI, GIANLUCA,CESTA, MARIA CANDIDA
申请号：
CA2737099
公开号：
CA2737099C
申请日:
2009.09.18
申请国别(地区):
CA
年份:
2016
代理人:
摘要：
The present invention relates to (R,S) 2-aryl-propionic acids and derivatives,their singleenantiomer (S) and to pharmaceutical compositions containing them, which areused inthe prevention and treatment of tissue damage due to the exacerbatedrecruitment ofpolymorphonucleated neutrophils (PlvTN leukocytes) at inflammation sites. Thepresent invention provides compounds for use in the treatment of transientcerebralischemia, bullous pemphigo, rheumatoid arthritis, idiopathic fibrosis andglomerulonephritis and damages caused by ischemia and reperfusion (Formula(I))(see formula I)
