ALLEGRETTI MARCELLO,ARAMINI ANDREA,BIANCHINI GIANLUCA,CESTA MARIA CANDIDA
申请号:
IN2422/CHENP/2011
公开号:
IN2011CN02422A
申请日:
2011.04.11
申请国别(地区):
IN
年份:
2012
代理人:
摘要:
The present invention relates to (R, S) 2-aryl-propionic acids and derivatives, their single enantiomer (S) and to pharmaceutical compositions containing them, which are used in the prevention and treatment of tissue damage due to the exacer-bated recruitment of polymorphonucleated neutrophils (PMN leukocytes) at inflammation sites. The present invention provides compounds for use in the treatment of transient cerebral ischemia, bullous pemphigo, rheumatoid arthritis, idiopathic fibrosis, glomerulonephritis and damages caused by ischemia and reperfusion.