CUTSHALL, NEIL, S.,GAGE, JENNIFER, LYNN,WHEELER, THOMAS, NEIL,LITTLE, THOMAS, L.
申请号：
EP11754087
公开号：
EP2544679A4
申请日:
2011.03.10
申请国别(地区):
EP
年份:
2014
代理人:
摘要：
Compounds that inhibit PDE10 are disclosed that have utility in the treatment of a variety of conditions, including (but not limited to) psychotic, anxiety, movement disorders and/or neurological disorders such as Parkinsons disease, Huntingtons disease, Alzheimers disease, encephalitis, phobias, epilepsy, aphasia, Bells palsy, cerebral palsy, sleep disorders, pain, Tourettes syndrome, schizophrenia, delusional disorders, drug-induced psychosis and panic and obsessive-compulsive disorders. Pharmaceutically acceptable salts, stereoisomers, solvates and prodrugs of the compounds are also provided. Also disclosed are compositions containing a compound in combination with a pharmaceutically acceptable carrier, as well as methods relating to the use thereof for inhibiting PDE10 in a warm-blooded animal in need of the same.
