CUTSHALL NEIL S,GAGE JENNIFER LYNN,WHEELER NEIL THOMAS
申请号:
IN1531/DELNP/2011
公开号:
IN2011DN01531A
申请日:
2011.03.03
申请国别(地区):
IN
年份:
2012
代理人:
摘要:
Compounds that inhibit PDE10 are disclosed that have utility in the treatment of a variety of conditions, including (but not limited to) psychotic, anxiety, movement disorders and/or neurological disorders such as Parkinsons disease, Huntingtons disease, Alzheimers disease, encephalitis, phobias, epilepsy, aphasia, Bells palsy, cerebral palsy, sleep disorders, pain, Tourettes syndrome, schizophrenia, delusional disorders, drug-induced psychosis and panic and obsessive-compulsive disorders. Pharmaceutically acceptable salts, stereoisomers, solvates and prodrugs of the compounds are also provided. Also disclosed are compositions containing a compound in combination with a pharmaceutically acceptable carrier, as well as methods relating to the use thereof for inhibiting PDE10 in a warm- blooded animal in need of the same.