DEFECTIVE SINDBIS VIRAL VECTORS

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专利权人:

NEW YORK UNIVERSITY

发明人:

HURTADO, ALICIA,艾麗西婭.烏爾塔多,MERUELO, DANIEL,丹尼爾.梅魯埃洛

申请号：

HK08106367.4

公开号：

HK1115811B

申请日:

2008.06.10

申请国别(地区):

HK

年份:

2014

代理人:

摘要：

Disclosed herein are new defective Sindbis viral vectors made from wild type Ar-339 Sindbis virus, with differences in replicase and envelope proteins between JT vectors and consensus Sindbis virus sequences, and also between JT and Ar-339 vectors. Also disclosed are plasmids used for the production of the vectors, methods for producing the vectors, methods for treating mammals suffering from tumors and pharmaceutical formulations for use in the treatment methods.

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