KIM, Seung-Kook,김승국,YOON, Moung Seok,윤명석,WON, Bo Ryoung,원보령
申请号：
KRKR2015/006378
公开号：
WO2016/013772A1
申请日:
2015.06.23
申请国别(地区):
WO
年份:
2016
代理人:
摘要：
The present invention relates to a hydrogel composition using a phase inversion temperature (PIT) emulsification process and to a production method for same. More specifically, the invention relates to a method wherein a water-based moiety comprising a water-soluble gelling polymer, purified water, a polyhydric alcohol and other additives is heated/stirred at between 60 and 100°C and, in a separate container, an oil-based moiety comprising a nonionic surfactant and an oily skin-softening agent is heated to between 60 and 95°C, and then the water-based moiety and the oil-based moiety are mixed and cooled to a temperature range at which the water-based moiety gells, namely between 60 and 80°C, and at the same time a PIT emulsion is stably impregnated into the gelled article, cooling takes place via a cooler, and a hydrogel is moulded. The present invention makes it possible to achieve more effective skin penetration of active ingredients in the nano-emulsion state, and thus to enhance the effects thereof, by using the PIT emulsification method to make it easier to include oil fractions in hydrogels in which it has previously been difficult to include oil fractions.La présente invention concerne une composition dhydrogel utilisant un procédé démulsification par température dinversion de phase (PIT), et le procédé de production associé. Plus spécifiquement, linvention concerne un procédé selon lequel une phase aqueuse comprenant un polymère soluble dans leau pouvant se gélifier, de leau purifiée, un alcool polyhydrique et dautres additifs est chauffée/agitée à une température comprise entre 60 et 100 °C et, dans un récipient séparé, une phase huileuse comprenant un tensioactif non ionique et un agent huileux dadoucissement de la peau est chauffé à une température comprise entre 60 et 95 °C. La phase aqueuse et la phase huileuse sont ensuite mélangées puis refroidies à la plage de température à laquelle la phase aqueuse se gélifie, cest-à-dire entre 60 et 80 °C, et, pend
