PROBLEM TO BE SOLVED: To provide an isoliquiritigenin composition having liquiritigenin pharmacological effect.SOLUTION: An isoliquiritigenin composition is characterized by obtaining liquiritigenin by treating isoliquiritigenin in acidic organic acid aqueous solution mainly composed of organic acid via the reaction represented by the following reaction formula. Preferably, the organic acid aqueous solution comprises citric acid as a main component and has a pH of 3.5 to 4.5.SELECTED DRAWING: Figure 1