An ultrasound image diagnosis apparatus and a method for setting an ultrasound drive voltage by which appropriate probe motion parameters are established by individually estimating temperature changes which occur due to a plurality of heat sources existing within the probe. By individually storing or correcting relative temperature change data associated with motion parameters due to a plurality of heat source elements, an optimum driving voltage for the ultrasound transducers is set. Since a transmission drive voltage is larger than the conventional drive voltage can be set under a permissible probe temperature, image diagnosis can be improved.