LUND, Kaare,BRIMNES, Jens,HENMAR, Helene,IPSEN, Hans-Henrik,MÆRKEDAHL, Lise Lund,HANSEN, Gitte Nordskov,MONSALVE CLEMENTE, Rafael Ignacio
申请号：
DK13716305
公开号：
DK2838556T3
申请日:
2013.04.16
申请国别(地区):
DK
年份:
2017
代理人:
摘要：
The invention relates to the treatment of a hypersensitivity immune response caused by a non-profilin allergen of a profilin-containing plant material (e.g. grass or tree pollen) by bystander suppression with a plant profilin (e.g. Phl p 12, Bet v 2, or Ole e 2) or a variant thereof. Also the invention features a particular variant of Phl p 12 with two of its cysteine residues replaced with another amino acid to increase its pharmaceutical properties.
