Lund, Kaare,Brimnes, Jens,Henmar, Helene,Ipsen, Hans-Henrik,Maerkedahl, Lise Lund,Hansen, Gitte Nordskov,Monsalve Clemente, Rafael Ignacio
申请号:
AU2013248275
公开号:
AU2013248275B2
申请日:
2013.04.16
申请国别(地区):
AU
年份:
2017
代理人:
摘要:
The invention relates to the treatment of a hypersensitivity immune response caused by a non-profilin allergen of a profilin-containing plant material (e.g. grass or tree pollen) by bystander suppression with a plant profilin (e.g. Phl p 12, Bet v 2, or Ole e 2) or a variant thereof. Also the invention features a particular variant of Phl p 12 with two of its cysteine residues replaced with another amino acid to increase its pharmaceutical properties.