Beijing An Jian Xi Bio-Medical Technology Co.; Ltd.
发明人:
Ruiqiong Ran
申请号:
US15547013
公开号:
US10494341B2
申请日:
2016.01.25
申请国别(地区):
US
年份:
2019
代理人:
摘要:
Disclosed are a compound as shown by the following formula 1, and a pharmaceutically acceptable salt, an ester, a hydrate and an organic solvate thereof. In the formula (1), the groups R1 to R17 are independently selected from the group consisting of hydrogen, fluorine, chlorine, bromine, iodine, C1-C8 alkyl, C1-C8 alkoxy, carbonyl, hydroxyl, amino, azido, carboxyl and C1-C8 alkylsulfinyl, respectively; and X is a carbon or nitrogen atom; Y is selected from the following groups: a single bond, C1-C8 alkylene, C6-C20 arylene and C4-C20 heteroarylene; and n is an integer from 5 to 20. Also provided in the present invention are a pharmaceutical composition containing the compound, and use thereof in the field of tumor therapy.