Modified von willebrand factor

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专利权人:

CSL Limited

发明人:

Wilson, Michael,Dower, Steve,Hartman, Dallas,Hardy, Mathew

申请号：

AU2015283822

公开号：

AU2015283822A1

申请日:

2015.07.02

申请国别(地区):

AU

年份:

2017

代理人:

摘要：

The present invention provides a modified polypeptide which binds Factor VIII. The modified polypeptide comprises a sequence as shown in SEQ ID NO:3 in which the sequence comprises at least a modification at position 1 or 3 such that the modified polypeptide binds to Factor VIII with an off rate at least 5 fold lower than a reference polypeptide comprising an unmodified SEQ ID NO:3.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/