SARUTA, Kunio,HAYASHI, Norimitsu,SAKURAI, Osamu,SAWAMOTO, Hiroaki,OBOKI, Eri
申请号：
ES13804940
公开号：
ES2690315T3
申请日:
2013.06.14
申请国别(地区):
ES
年份:
2018
代理人:
摘要：
Compound represented by the general formula (1): ** Formula ** in which ring A is benzene which may be substituted with 1 to 3 linear or branched C1-8 alkyl group (s)； or 6-membered monocyclic aromatic heterocycle which may be substituted with 1 to 3 linear or branched C1-8 alkyl group (s): Ring B is benzene which may be substituted with 1 to 3 substituent group (s) selected (s) from linear or branched C1-8 alkyl, halogen and cyano； or 6-membered monocyclic aromatic heterocycle which may be substituted with 1 to 3 substituent group (s) selected from linear or branched C1-8 alkyl, halogen and cyano: X is a single bond or -O- : Y is (a) linear or branched C1-8 alkyl which includes a group having 2 substituent groups on the same alkyl carbon atom, and in which the 2 substituent groups form a ring together with the adjacent carbon and which is substituted with 1 to 3 substituent group (s) that is selected from (i) aminocarbonyl which may be substituted with linear or branched C1-8 alkyl which may be substituted with 1 to 3 hydroxyls, and ( ii) carboxyl； or (b) C3-8 cycloalkyl which is substituted with 1 to 3 substituent group (s) selected from linear or branched C1-8 alkyl substituted with carboxyl, carboxyl, linear C1-8 alkyl or branched substituted with linear or branched C1-8 alkoxy and aminocarbonyl； Z is CR1 or nitrogen atom: R1 is hydrogen, halogen atom, linear or branched C1-8 alkoxy or linear or branched C1-8 alkyl which may be substituted with 1 to 6 halogen atom (s): (i) when Z is CR1, R2 is the formula below: ** Formula ** in which Z 'represents a single bond, C1-8 alkylene, -Alk-O-, or -Alk1-O-Alk2-, in which Alk, Alk1 and Alk2 each independently represent C1-6 alkylene, and the link at the far right represents a link to the C ring, the C ring represents an aromatic, monocyclic, bicyclic or tricyclic hydrocarbon group of 6 to 14 members or a group 5 to 14-membered aromatic, monocyclic or bicyclic heterocyclic heterocyclic, R3 and R4 each independently repres
