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CHOLINE FENOFIBRATE DELAYED RELEASE COMPOSITIONS
专利权人:
Bernard Charles Sherman
发明人:
Bernard Charles Sherman
申请号:
US13395141
公开号:
US20120225946A1
申请日:
2010.09.09
申请国别(地区):
US
年份:
2012
代理人:
摘要:
Described are solid pharmaceutical compositions for oral administration comprising choline fenofibrate and an amount of an acid sufficient to substantially reduce a rate of dissolution of choline fenofibrate in an aqueous environment at pH 4.5 to less than about 50% in 2 hours. Processes for making the solid pharmaceutical composition for oral administration comprising: (a) mixing choline fenofibrate with an amount of an acid sufficient to substantially reduce a rate of dissolution of choline fenofibrate in an aqueous environment at pH 4.5 to less than about 50% in 2 hours and (b) preparing a dosage form suitable for oral administration are also provided.
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