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NOUVEAUX CO-CRISTAUX DE CHOLINE ET D'ÉPALRESTAT
专利权人:
Inc.;Bionevia Pharmaceuticals
发明人:
申请号:
EP09812208.8
公开号:
EP2326632B1
申请日:
2009.09.03
申请国别(地区):
EP
年份:
2017
代理人:
摘要:
The invention relates to a novel choline cocrystal of 5-[(1Z,2E)-2-methyl-3-phenylpropenylidene]-4-oxo-2-thioxo-3-thiazolidineacetic acid. The preparation and characterization of the novel choline cocrystal according to various embodiments of the invention is described. The invention also relates to pharmaceutical compositions containing the novel choline cocrystal and the therapeutic use of the novel choline cocrystal to treat and/or prevent various conditions, including treating and/or preventing diabetic complications, treating and/or preventing homocystinuria reducing levels of homocysteine in blood serum, inhibiting aldose reductase, and affording cardioprotection in non-diabetic patients.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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