EXTRACTION FRACTION CONTAINING POLYMER CONDENSATION TANNIN OBTAINED FROM EPHEDRA EXTRACT OR EPHEDRINE ALKALOIDS-FREE EPHEDRA HERB EXTRACT, AND METHOD OF PRODUCING THE SAME AND USE THEREOF农业专利-农业专业知识服务系统

专利权人:: KITASATO INSTITUTE;学校法人北里研究所;KOKURITSU IYAKUHIN SHOKUHIN EISEI KENKYUSHO;国立医薬品食品衛生研究所長;MATSUYAMA UNIV EDUCATIONAL CORP;学校法人松山大学;TOKIWA SHOKUBUTSU KAGAKU KENKYUSHO:KK;株式会社常磐植物化学研究所;ZERIA PHARMACEUTICAL

发明人:: HANAWA TOSHIHIKO,花輪壽彦,HYUGA SUMIKO,日向須美子,ODAGUCHI HIROSHI,小田口浩,KOBAYASHI YOSHINORI,小林義典,NAKAMORI SHUNSUKE,中森俊輔,AIDA YUKIHIRO,合田幸広,HYUGA SHOJI,日向昌司,HAKAMAZUKA TAKASHI,袴塚高志,OSHIMA NAOHIR

摘要：: To provide a pharmaceutical that has an anticancer action and anti-metastasis action through a c-Met kinase inhibitory action, a pain inhibitory action, and an anti-influenza virus action, and eliminates side effects of ephedrine alkaloid.SOLUTION: The present invention provides an extraction fraction containing a polymer condensation tannin with a weight average molecular weight of 45,000 or more derived from Ephedra extract or Ephedrine alkaloids-free Ephedra herb extract (EFE), and a pharmaceutical composition containing the polymer condensation tannin with a weight average molecular weight of 45,000 or more by 30% or more.SELECTED DRAWING: None【課題】c-Metキナーゼ阻害作用を介する抗がん作用・抗転移作用、疼痛抑制作用、及び抗インフルエンザウイルス作用を有し、エフェドリンアルカロイドによる副作用を排除した医薬品の提供。【解決手段】麻黄エキス由来、又はエフェドリンアルカロイド除去麻黄エキス（EFE）由来の重量平均分子量45,000以上の高分子縮合型タンニンを含む抽出分画物であって、前記重量平均分子量45,000以上の高分子縮合型タンニンを30%以上含む抽出分画物を含む医薬組成物。【選択図】なし