Brian Budzik,David Gwyn Cooper,Ian Thomson Forbes,Jian Jin,Dongchuan Shi,Paul William Smith,Graham Walker
申请号:
US12088489
公开号:
US08288413B2
申请日:
2006.09.27
申请国别(地区):
US
年份:
2012
代理人:
摘要:
Compounds of formula (I) and salts are provided:wherein R6 is selected from hydrogen, halogen, C1-6alkyl, C1-6alkyl substituted with one or more fluorine atoms, C3-6cycloalkyl, C3-6cycloalkyl substituted with one or more fluorine atoms, C1-6 alkoxy, C1-6 alkoxy substituted with one or more fluorine atoms, and cyano, and Q is hydrogen or C1-6alkyl. The compounds are M1 agonists and are useful for therapy, for example in the treatment of psychotic disorders and cognitive impairment.