APELIOTUS TECHNOLOGIES, INC.;MASSACHUSETTS EYE AND EAR INFIRMARY
发明人:
John G. EDWARDS,Joan W. MILLER,Demetrios VAVVAS
申请号：
US16756588
公开号：
US20200243170A1
申请日:
2018.10.17
申请国别(地区):
US
年份:
2020
代理人:
摘要：
Methods of using visual functions such as dark adaptation, low luminance visual acuity, low luminance deficit, contrast sensitivity and scotopic sensitivity as functional biomarkers for statin therapy in AMD. These biomarkers can be used, for example, to support clinical trials of statin therapy for AMD by identifying participants more likely to respond, by providing an early indication of response, or by serving as an endpoint； or to support treatment of AMD patients with statins by identifying patients more likely to respond, by providing an early indication of responders vs. non-responders, or by confirming a treatment benefit.
