PHARMACEUTICAL COMPOSITION FOR PREVENTING OR TREATING DIABETES MELLITUS, METHOD FOR PREVENTING OR TREATING DIABETES MELLITUS, AND METHOD FOR SCREENING FOR DIABETES MELLITUS THERAPEUTIC AGENT
UNIVERSITY-IN-DUSTRY COOPERATION GROUP OF KYUNG HEE UNIVERSITY
发明人:
Hyeung Jin JANG
申请号：
US14908210
公开号：
US20160175263A1
申请日:
2014.08.01
申请国别(地区):
US
年份:
2016
代理人:
摘要：
Provided are a pharmaceutical composition including geraniol or a pharmaceutically acceptable salt thereof as an active ingredient for use in preventing or treating diabetes mellitus, a method of preventing or treating diabetes mellitus or a complication due to diabetes mellitus of an individual, in which the method includes administering the individual with a pharmaceutical composition comprising geraniol or a pharmaceutically acceptable salt thereof as an active ingredient and inducing an olfactory stimulation to the individual using the pharmaceutical composition, and a screening method of an antidiabetic agent that may include contacting a cell expressing an olfactory receptor with a test material； measuring a level of expression of glucagon-like peptide-1 (GLP-1) secreted from the cell； and determining the test material, when the test material promotes expression of GLP-1, as a candidate material of an antidiabetic agent. In addition, a quasi-drug composition and a cosmetic composition including geraniol for uses are provided.
