Ekambar R. Kandimalla,Daqing Wang,Ireneusz Nowak,Sudhir Agrawal
申请号：
US14791749
公开号：
US20160215287A1
申请日:
2015.07.06
申请国别(地区):
US
年份:
2016
代理人:
摘要：
The invention provides novel immune regulatory oligonucleotides (IRO) as antagonist of TLRs and methods of use thereof. These IROs have unique sequences that inhibit or suppress TLR-mediated signaling in response to a TLR ligand or TLR agonist. The methods may have use in the prevention and treatment of cancer, an autoimmune disorder, airway inflammation, inflammatory disorders, infectious disease, skin disorders, allergy, asthma or a disease caused by a pathogen.
