An external end device for permanent catheters comprises a container (5) that houses two taps (26 27) being provided with knobs (8 9) and having at one hand a first connector (23) for the connection to the catheters (2) and at the other hand second connectors (12 13) projecting from the container for the connection to an external equipment. The first connector (23) is connected to the catheter (2) by a coupling (4) exiting the container (5) and externally holding a subcutaneous cuff (3) designed to be positioned in the subcutaneous tissue of the patient’s body. The second connectors (12 13) are provided with caps (14 15) surrounded by the disposable absorbent material (73) being received in the closure lid (20) and having spaces (16 17) for housing the caps for protecting them externally from a bacterial attack by means of the antiseptic substance by which it is impregnated.