YEDA RESEARCH AND DEVELOPMENT CO. LTD. AT THE WEIZ
发明人:
GIDEON SCHREIBER,LAILA C. ROISMAN,DIEGO JAITIN,EYAL KALIE
申请号:
HK09104314.2
公开号:
HK1125317B
申请日:
2009.05.11
申请国别(地区):
HK
年份:
2014
代理人:
摘要:
The present invention provides IFN±2 mutants and active fragments, analogs, derivatives, and variants thereof that have improved specific agonist or antagonist activity as compared to wild-type IFN±2. The present invention further provides pharmaceutical compositions comprising IFN±2 mutants useful for treating or preventing cancer, autoimmune diseases, infectious diseases or disorders associated with increased expression of IFN±2.