Yeda Research and Development Co. Ltd. at the Weizmann Institute of Science
发明人:
Kalie, Eyal,Jaitin, Diego,Schreiber, Gideon,Roisman, Laila C.
申请号：
AU2006263331
公开号：
AU2006263331B2
申请日:
2006.06.28
申请国别(地区):
AU
年份:
2012
代理人:
摘要：
The present invention provides IFNα2 mutants and active fragments, analogs,derivatives, and variants thereof that have improved specific agonist or antagonistactivity as compared to wild-type IFNα2. The present invention furtherprovides pharmaceutical compositions comprising IFNα2 mutants usefulfor treating or preventing cancer, autoimmune diseases, infectious diseasesor disorders associated with increased expression of IFNα2.
