Humanwell Healthcare (Group) Co., Ltd.;Hubei Bio-Pharmaceutical Industrial Technological Institute Inc.
发明人:
申请号:
EP16861623.3
公开号:
EP3372594A4
申请日:
2016.11.04
申请国别(地区):
EP
年份:
2019
代理人:
摘要:
The present invention provides a pyrimidine derivative and a use thereof. The pyrimidine derivative is the compound shown in formula I or a pharmaceutically acceptable salt, hydrate, solvate, metabolite or prodrug thereof, wherein, R 1 , R 2 , R 3 , R 4 and R 5 are, for example, as defined in the specification. The compound can act as an ALK inhibitor, and is for preparing an anti-tumor medicament for suppressing an anaplastic lymphoma kinase.