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PYRIMIDINE DERIVATIVE AND USE THEREOF
专利权人:
Hubei Bio-Pharmacutical Industrial Technological Institute Inc.;Humanwell Healthcare (Group) Co., Ltd.
发明人:
Xuehai Wang,Yong Xu,Xijun Sheng,Xiaolin Zhang,Hangui Xia,Zhongwen Yang,Yang Yue,Lu Huang,Qiang Xiao
申请号:
US15773826
公开号:
US20180338973A1
申请日:
2016.11.04
申请国别(地区):
US
年份:
2018
代理人:
摘要:
The present invention provides a pyrimidine derivative and a use thereof. The pyrimidine derivative is the compound shown in formula I or a pharmaceutically acceptable salt, hydrate, solvate, metabolite or prodrug thereof, wherein, R1, R2, R3, R4 and R5 are, for example, as defined in the specification. The compound can act as an ALK inhibitor, and is for preparing an anti-tumor medicament for suppressing an anaplastic lymphoma kinase.
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