Haeng Woo Lee,Hyeon Cheol Shin,Seoung Ho Kim,Yong Ju Park
申请号:
US13689311
公开号:
US20130084330A1
申请日:
2012.11.29
申请国别(地区):
US
年份:
2013
代理人:
摘要:
Disclosed is a composition for treating arthritis containing a dibenzo-p-dioxin derivative as an active ingredient. This dibenzo-p-dioxin derivative is very effective in inhibiting NF-kB and AP-1 activity, alleviates the symptoms of degenerative arthritis and rheumatoid arthritis without irritating the skin or causing side effects, and can continue to exhibit improvement effects for a considerable period of time after discontinuation of treatment. Additionally, when the dibenzo-p-dioxin derivative is contained in liposomes, the composition of the invention exhibits much greater effects on treating arthritis by absorption through skin, and thus is useful for the treatment of degenerative arthritis and rheumatoid arthritis.