ROBERTS, Bruce L.,SHANKARA, Srinivas,BRONDYK, William Harold,SIDERS, William M.
申请号：
AU2015207936
公开号：
AU2015207936A1
申请日:
2015.07.31
申请国别(地区):
AU
年份:
2015
代理人:
摘要：
#$%^&*AU2015207936A120150827.pdf#####\bstract: The present invention relates to humanized immunoglobulins, mouse monoclonal antibodies and himeric antibodies that have binding specificity for human CD52. The present invention further relates o a humanized immunoglobulin light chain and a humanized immunoglobulin heavy chain. The invention iso relates to isolated nucleic acids, recombinant vectors and host cells that comprise a sequence which ncodes a humanized immunoglobulin or immunoglobulin light chain or heavy chain, and to a method of reparing a humanized immunoglobulin. The humanized immunoglobulins can be used in therapeutic pplications to treat, for example, autoimmune disease, cancer, non-Hodgkins lymphoma, multiple clerosis and chronic lymphocytic leukemia.
