The present invention addresses the problem of providing a novel compound which has an antagonistic activity against a retinoid-related orphan receptor [gamma] and can exhibit a therapeutic or prophylactic effect on an autoimmune disease such as psoriasis. The present invention provides a cyclic amine derivative (I) typified below, a stereoisomer or hydrate of the derivative, or a pharmacologically acceptable salt of the derivative or the stereoisomer or hydrate.本發明係以提供一種新穎化合物作為目的，該新穎化合物具有類視色素相關孤兒受體γ拮抗劑活性，而對乾癬等之自體免疫疾病發揮治療效果或預防效果。本發明提供下述所代表之環狀胺衍生物(I)、其立體異構物或者此等之水合物、或彼等之藥理學容許鹽。
