六氫菸鹼酸衍生物及其醫藥用途农业专利-农业专业知识服务系统

发明人:: NISHIMURA, YUTAKA,西村裕,KATO, YUKO,加藤佑子,加藤祐子,HAYASHI, SHINNOSUKE,林新之助,YAMAZAKI, AIKO,山崎亚衣子,山崎亞衣子,YAMAMOTO, MASASHI,山本将史,山本將史,ASAOKA, YOSHIJI,浅冈由次,淺岡由次,YAMADA, MASATERU,山田将辉,山田將輝,YAMADA, NAOHIRO

摘要：: The purpose of the present invention is to provide compounds showing sEH inhibitory activity, and to provide medicines can exert preventive effect and therapeutic effect on chronic kidney disease and pulmonary hypertension based on the inhibition of sEH. The present invention provides nipecotic acid derivative represented by the following formula or pharmacologically acceptable salts thereof.本發明之目的係提供一種顯示sEH抑制活性之化合物，並同時提供一種醫藥，其根據sEH之抑制作用，而發揮針對慢性腎臟病及肺高血壓症之治療效果及預防效果，本發明係提供下述化學式所代表之六氫菸鹼酸衍生物或其藥理學上容許之鹽。