METHODS AND COMPOSITIONS FOR HETEROLOGOUS REPRNA IMMUNIZATIONS

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专利权人:

Janssen Vaccines & Prevention B.V.;Massachusetts Institute of Technology

发明人:

VOGELS, Ronald,VAN DER NEUT KOLFSCHOTEN, Marijn,IRVINE, Darrell J.,WEISS, Ron,PORTER, Ely Blanton,MELO, Mariane Bandeira,KITADA, Tasuku

申请号：

SG11202000019R

公开号：

SG11202000019RA

申请日:

2018.07.27

申请国别(地区):

SG

年份:

2020

代理人:

摘要：

Compositions and methods are described for inducing an immune response against an immunogen in humans. The induced immune response is obtained by administering a heterologous prime-boost combination of an in vitro transcribed (IVT) self-replicating RNA (repRNA) and an adenovirus vector. The compositions and methods can be used to provide a protective immunity against a disease, such as a viral infection or a cancer, in humans.

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中国工程科技知识中心

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