The application relates to the methods for preventing, treating, or reducing an infection by phytopathogenic, facultative saprophytic or saprotrophic microbes (e.g. phytopathogenic fungi) in a consumable product or on surfaces in contact with a consumable product comprising contacting them with a composition containing nootkatone and optionally an additional active ingredient; or comprising applying said composition to a vector pest. The application further relates to the compositions comprising nootkatone and optionally an additional active ingredient.