DEMUTH, HANS-ULRICH,HEISER, ULRICH,HOFFMANN, TORSTEN,NIESTROJ, ANDRÉ J.,SCHILLING, STEPHAN
申请号：
DK10159763
公开号：
DK2206496T3
申请日:
2004.05.05
申请国别(地区):
DK
年份:
2014
代理人:
摘要：
The present invention provides novel physiological substrates of mammalian glutaminyl cyclase (QC, EC 2.3.2.5), new effectors of QC, methods for screeing for such effectors, and the use of such effectors and pharmaceutical compositions comprising such effectors for the treatment of conditions that can be treated by modulation of QC-activity. Preferred compositions additionally comprise inhibitors of DP IV or DP IV-like enzymes for the treatment or alleviation of conditions that can be treated by modulation of QC- and DP IV-activity.
