A live or inactivated recombinant vaccine is described, comprising a viral vector and a pharmaceutically acceptable vehicle, adjuvant and/or excipient, wherein the viral vector is capable of generating a cell immune response due to an increased alpha and/or gamma interferon production, and is capable of a quick replication, and it has inserted a nucleotide sequence of the ORF 5 and ORF 6 from PRRS.本發明係有關於一種活性或去活性重組疫苗,包括一病毒載體以及一醫藥上可接受之載體、佐劑、及/或賦型劑,其中,該病毒載體係藉由增加α及/或γ干擾素以產生細胞免疫反應,並具有快速複製的能力,且該病毒載體插入來自豬生殖與呼吸綜合症(PRRS)之一核苷酸序列ORF 5以及ORF 6。