MÉTHODE DE DIFFÉRENCIATION DE CELLULES CARTILAGINEUSES, DE CELLULES OSSEUSES, DE CELLULES NERVEUSES OU D'ADIPOCYTES À PARTIR DE CELLULES STROMALES MÉSENCHYMATEUSES HUMAINES DU CORNET INFÉRIEUR
Catholic University Industry Academic Cooperation Foundation
发明人:
申请号：
EP11759703.9
公开号：
EP2551342B1
申请日:
2011.03.22
申请国别(地区):
EP
年份:
2018
代理人:
摘要：
The present invention relates to a method for inducing differentiation of human inferior turbinate mesenchymal stromal cells to bone cells, cartilage cells or nerve cells. More particularly, the present invention relates to a method for inducing differentiation of human inferior turbinate mesenchymal stromal cells to bone cells, cartilage cells, nerve cells or fat cells, wherein the method comprises the step of culturing the mesenchymal stromal cells that are isolated from human inferior turbinate tissues in a medium containing growth factors. The present invention also relates to a composition for prevention or treatment of cartilage injury or disease, bone injury or osseous metabolic disease, or nerve injury or disease that contain cells differentiated by said method as active ingredients. The bone cells, cartilage cells, nerve cells or fat cells differentiated from human inferior turbinate mesenchymal stromal cells according to the present invention can be used in the fields of cell replacement therapy and regenerative medicine for treating diseases caused by the damage of said cells, and the human inferior turbinate tissues used in the present invention can be easily obtained as the source of the cells from the discarded tissues during inferior turbinate surgery.
