An isolation apparatus for transporting and storing objects or human remains. The apparatus is formed of a flexible, foldable, opaque, generally box-like enclosure fabricated of a fiber reinforced plastic film, and welded together to form a sealed, air-tight and/or liquid-tight enclosure. A gas and liquid sealing zipper is positioned along three of four sides of the enclosure, thereby allowing the apparatus to open in a clamshell or suitcase-like manner, for easy access to the interior of the enclosure. An NBC and/or a CBRN filter can be mounted to the apparatus to allow for release of pressure from within the enclosure. An interior liner made of chemical protective fabric can be placed within the enclosure for additional chemical containment. This apparatus eliminates or significantly reduces the size and number of cracks, crevices and/or other voids into which contaminated materials can enter, for example by positioning, sizing and/or structuring welds to extend completely to an edge of the isolation apparatus, and/or by welding materials together entirely around one or more peripheries.
