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Methods and agents for the treatment of cancer
专利权人:
发明人:
申请号:
EP11177770.2
公开号:
EP2418219A1
申请日:
2004.10.15
申请国别(地区):
EP
年份:
2012
代理人:
摘要:
There is provided a polypeptide having a modified amino acid sequence compared to KEKLKSQWNNDNPLFK (SEQ ID No: 11), wherein the modified amino acid sequence has one or more amino acid substitutions and/or deletions compared to SEQ ID No. 11 and 60% sequence identity with SEQ ID No. 11 or greater, or comprises amino acid sequence KEKLKNPLFK (SEQ ID No. 10). There is also provided a polypeptide for use in the prophylaxis or treatment of a cancer in a mammal, wherein the polypeptide comprises the amino acid sequence KEKLKSQWNNDNPLFK (SEQ ID No: 11) or a modified form thereof having 60% sequence identity with the amino acid sequence or greater.
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