Коригодский Александр Робертович (RU),Захаров Иван Дмитриевич (RU)
申请号:
RU2013155972/15
公开号:
RU2013155972A
申请日:
2013.12.17
申请国别(地区):
RU
年份:
2015
代理人:
摘要:
1. A pharmaceutical preparation for the prevention and treatment of progressive myopia, which is an aqueous solution for instillation, or ophthalmic gel or eye drug film, comprising in its composition an effective amount of the amine with the functional groups in salt form, or as part of a complex of a transition metal compound, or smesi.2 them. A preparation according to claim 1, characterized in that the concentration of the salt or complex of a transition metal-based compound with amine functional groups in the solution is 0,15-7,0 wt.%. 3. A preparation according to claim 1, characterized in that as the aqueous medium used for the solution with distilled water or normal saline, or a smes.4. A preparation according to claim 3, characterized in that with an isotonic saline solution or balanced selected saline BBS and / or aqueous solutions of nonionic compounds, such as glycerol or sorbitol or mannitol or propylene glycol, or dekstroza.5. A preparation according to claim 1, characterized in that the aqueous solution further comprises geleobrazovatel.6. A preparation according to claim 5, characterized in that the gelling agent is used as hyaluronic acid, chondroitin sulfate, or polyvinyl alcohol, or methylcellulose, or hydroxyethyl cellulose, or hydroxypropylcellulose, or hydroxypropyl or polyethylene glycol-polypropylene glycol-polyethylene glycol block copolymer or a Na-carboxymethylcellulose, or salt of crosslinked polyacrylic acid and its copolymers with C10-30-alkyl acrylates or their smes.7. A preparation according to claims 5 and 6, characterized in that the gelling agent content in the aqueous solution is 0,1-25,0 wt.%. 8. A drug1. Фармацевтический препарат для профилактики и лечения прогрессирующей близорукости, представляющий собой водный раствор для инстилляций, или глазной гель, или глазную лекарственную пленку, содержащий в своем составе эффективное количество амина с функциональными группами в виде соли, или в составе комплексного соединения переходн