Azaheteroc u00edclica amino substituted carboxamide Compounds, their manufacture and their use for the treatment of diseases such as cancer hiperproiiferativas.Claim 1, characterized because it responds to a compound of formula (1) and to pharmaceutically acceptable salts, solvates and prodrugs thereof, where X is n or C - R3, and NH, or is absent, is L1 - L2 R1 - R4 R5 R6 - L3, L1 - L2 - R4 R4 R5 L1 or R2, R2 ',' 'each independently between If you are h, Hal, OA, Oh, NH2, sh, CN, NO2, Nha, NH - l1 - AR - AR - nhco nhcoa, L1, L1 nhso2a, nhso2 - AR,Nhconha nhconh L1 or L1 - AR - AR, -, or - AR - R4 L1, L1, L1, L3 each, independently of whether they are a Union simple alquileno unbranched or branched, with 1, 2, 3, 4 or 5 c Atoms which can not be replaced, or be mono - or alkylated with Hal, Oh, CN, NH2, NH (n), (2), NO2, COOH, Ethenyl or etinilo, N3, and / or imidazols with R4,And in which one or two CH2 groups can be replaced with an Atom or a Group - s or - NH, - N (-, -) with N - (-) - Coo -, or - nhco - SO2 -, R3 is H, Oh, Hal, COOH, NH2, sh, NO2 or CN, R4, R5, R6, each independently between themselves, are AR, monocyclic or rent with 3, 4, 5, 6 or 7 u00e1tom You RingIn which one or two CH2 groups can be replaced with an Atom or a group and / or - NH -, na - cha, co, CH = N or CH = CH, and / or in which the Connector can be replaced with CH Group a n Atom, and which may be mono - or di - or replaced with Hal, L2 is nhcoo nhco - - - - - - nhconh, Nhcona nhcoa - -, - -, - O -, - S -.Nhso2, - NH -, - - - - - - so2nh, with conhconh, - - - - - - nhconhco or, ar is a homo - or mono - or bicyclic Aromatic heterocycle with 0, 1, 2, 3 or 4 Atoms of N, o and S and / or 5 6, 7, 8, 9, or 10 Atoms in the Skeleton, which can not be replaced or, IF be independently between mono -, di - or tri s Ustituidos with Hal, Oh, NH2, sh, OA, Nha, Na2, NO2, OCN, CN, SCN, COOH, CONH2 conha cona2 COOA,,,,Nhcoa nhconha, nhconh2, nhso2a, Cho, COA, and / or so2hal so2nh2, SO2, and in whi
