The present invention relates to a manufacturing method for a liquid high-purity glycerin derivative-modified silicone, the method comprising: a step of adding, to a mixture containing a glycerin derivative-modified silicone and impurities, an organic wax having affinity with the impurities and having a higher melting point than the glycerin derivative-modified silicone, melting and mixing while heating, and introducing the impurities into the melted organic wax a step of obtaining a solidified product of the organic wax by cooling the organic wax and a step of performing solid-liquid phase separation on the glycerin derivative-modified silicone and the solidified product of the organic wax. With the present invention, it is possible to provide a useful method for stably producing a high-purity glycerin derivative-modified silicone on a commercial scale.