UNIVERSIDADE ESTADUAL PAULISTA JULIO DE MESQUITA FILHO - UNESP;EMS S.A.
发明人:
Ednir de Oliveira VIZIOLI,Chung Man Chin,Renato Farina Menegon,Lorena Blau,Jean Leandro Dos Santos,Maria do Carmo Longo
申请号：
US14035690
公开号：
US20140057959A1
申请日:
2013.09.24
申请国别(地区):
US
年份:
2014
代理人:
摘要：
The present invention relates to compounds derived from taurine with non-steroidal anti inflammatory activity.In a first embodiment, the present invention relates to compounds derived from taurine, in which taurine is bound directly by means of an amide bond or through an spacing group, to a compound selected from the group of non-steroidal anti inflammatory compounds, cited as derived from taurine presenting the Formula (I):in which R means the component with non-steroidal anti inflammatory activity.In a second embodiment, the invention provides a process for obtaining the compounds of Formula (I) by reaction of taurine with a compound belonging to the group of non-steroidal anti inflammatory (NSAIs), in order to obtain a compound derived from taurine by direct bond or through a spacing group of the taurine to the NSAI.The invention also relates to the pharmaceutical compositions comprising at least one compound derived from taurine presenting non-steroidal anti inflammatory activity.
