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Compounds derived from taurine, process of their preparation and pharmaceutical compositions containing these
专利权人:
Chung M. Chin;Lorena Blau;Jean L. Santos;Renato F. Menegon;Ednir D. Vizioli;Maria D. Longo
发明人:
Ednir D. Vizioli,Chung M. Chin,Renato F. Menegon,Lorena Blau,Jean L. Santos,Maria D. Longo
申请号:
US12937188
公开号:
US08569335B2
申请日:
2009.04.09
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The present invention relates to compounds derived from taurine with non-steroidal anti inflammatory activity.In a first embodiment, the present invention relates to compounds derived from taurine, in which taurine is bound directly by means of an amide bond or through an spacing group, to a compound selected from the group of non-steroidal anti inflammatory compounds, cited as derived from taurine presenting the Formula (I):in which R means the component with non-steroidal anti inflammatory activity.In a second embodiment, the invention provides a process for obtaining the compounds of Formula (I) by reaction of taurine with a compound belonging to the group of non-steroidal anti inflammatory (NSAIs), in order to obtain a compound derived from taurine by direct bond or through a spacing group of the taurine to the NSAI.The invention also relates to the pharmaceutical compositions comprising at least one compound derived from taurine presenting non-steroidal anti inflammatory activity.
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