Keith T. Demarest;Patricia Pelton;Gee-Hong Kuo;Yan Zhang;Lan Shen;Songfeng Lu
发明人:
Gee-Hong Kuo,Yan Zhang,Lan Shen,Songfeng Lu,Keith T. Demarest,Patricia Pelton
申请号：
US12689335
公开号：
US08633184B2
申请日:
2010.01.19
申请国别(地区):
US
年份:
2014
代理人:
摘要：
The invention is directed to compounds of Formula (I) useful as PPAR agonists. Pharmaceutical compositions and methods of treating one or more conditions including, but not limited to, diabetes, nephropathy, neuropathy, retinopathy, polycystic ovary syndrome, hypertension, ischemia, stroke, irritable bowel disorder, inflammation, cataract, cardiovascular diseases, Metabolic X Syndrome, hyper-LDL-cholesterolemia, dyslipidemia (including hypertriglyceridemia, hypercholesterolemia, mixed hyperlipidemia, and hypo-HDL-cholesterolemia), atherosclerosis, obesity, and other disorders related to lipid metabolism and energy homeostasis complications thereof, using compounds of the invention are also described.
